ABSTRACT
The coronavirus pandemic (COVID-19), due to severe acute respiratory syndrome coronavirus-2, is a major current public health problem worldwide. It is crucial to recognize that recovery of patients with COVID-19 does not end with the hospital discharge but rather begins, and improving daily physical activity (PA) seems crucial to this recovery. Thus, characterizing PA in patients with COVID-19 after discharge should be a priority in public health. Furthermore, reporting the impact of COVID-19 on the functional status and PA in the long-running follow-up of patients would allow to understand the evolution and prognosis of the disease and develop a strategy of its management [1]. Hence, we aim to investigate PA and functional status in patients who suffered from COVID-19 across the severity of the disease. This paper describes the algorithm developed for the estimation of PA from data collected with an inertial measurement unit (IMU) and the preliminary results of the objective evidence of the improvement of activity level over time. © 2022 IEEE.
ABSTRACT
Objective: To describe and analyze case reports and published studies in which a possible relationship between COVID-19 and mucocutaneous lesions in the oral cavity and face is presented. Methodology: A review was performed in Pubmed, Google Scholar, ProQuest, and Medline Complete databases, 56 articles were selected reporting mucocutaneous manifestations in oral cavity and face associated to COVID-19. Results: We found 91 reported cases with mucocutaneous manifestations in oral cavity and face, associated with COVID-19. Eighteen percent of the patients presented lesions at both facial and oral levels. The cheeks were the most affected areas representing 16 % and of oral lesions the most affected site was the tongue with 26 %. Conclusion: According to the findings, the presence of mucocutaneous manifestations in face and oral cavity are associated with SARS-CoV-2 infection. It is expected that tissues with higher expression of ECA2 and TMPRSS2 are more susceptible to infection by SARS- CoV-2 and therefore present some type of lesion. Among the oral tissues with higher expression of these molecules, the tongue was described, which would favor a higher prevalence of lesions.
ABSTRACT
Introduction: Reports have revealed that people susceptible to severe forms of COVID-19 are older adults with comorbidities;However, the pediatric population has also been affected, considering children with underlying conditions such as onco-hematological conditions to be high risk. We present a cases series in a third level hospital. Material and methods: We conducted a retrospective study in children under the age of 16 years with a diagnosis of acute leukemia and infection with the SARS-CoV2 virus. Descriptive statistics with means and percentages were used. To show differences between the groups, Chi-square test, Student t test and Mann-Whitney U test were used depending on the type of variable and its distribution. Results: SARS-CoV2 virus infection was confirmed in 15 children diagnosed with acute leukemia, at different stages of treatment. The mean age was 7.5 years, 8 male and 7 female, 11 of them diagnosed with acute B-cell lymphoblastic leukemia, one with acute T-cell lymphoblastic leukemia and 3 with acute myeloid leukemia. The mean days of hospital stay at the diagnosis of COVID-19 was 22. Thirteen of the children had fever and neutropenia. 7 patients died. There was a statistically significant correlation with the outcome in patients who presented a prolongation of aPTT, an increase in D-dimer, an increase in liver enzymes and severe respiratory distress with the need for mechanical ventilation. Conclusion: The risk of death in children with leukemia and COVID-19 was associated with prolonged aPTT, increased D-dimer, increased liver enzymes, respiratory distress, and the need for mechanical ventilation.